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How about:

Sequel to Centauri Alliance, perhaps as an SRPG with a hex grid, though I'd be fine with another first person dungeon crawler.

SaGa Frontier 3, set in a space opera-type setting; I'm thinking something like Isaac Asimov's Foundation series would work here. The game would be structured like SaGa Frontier 2 (with perhaps a few tweaks to deal with some of the biggest flaws of that system), but would feature futuristic settings and multiple races with different growth rules like the original SaGa Frontier.

Wizardry 9, of course. (This game would play like the later Sir-Tech Wizardries, perhaps most resembling 8, as opposed to the Japanese spin-offs.)

A prequel to Final Fantasy 5, featuring the Warriors of Dawn. Final Fantasy 6 is also ripe for a prequel.

A sequel to Final Fantasy 6 that focuses on rebuilding the world.

A remake of Dragon Quest 6 in which Sensei from SaGa 2 (Mr.S in FFL2) is recruitable. (It felt like a missed opportunity; they released the SaGa 2 remake in Japan for the anniversary (25th?) of the series, and DQ6's remake appeared around the same time and had recruitable slimes, so why not have that slime from SaGa 2 (who looks like a SaGa 1 slime, actually) makae a playable cameo appearance?)

A sequel to Final Fantasy 4 that is not The After Years, but instead tells a different approach, perhaps featuring Cecil's daughter (he didn't have a son in this timeline). Actually, I think that game developers shouldn't focus on having a single canon timeline, and should instead not be afraid to have multiple sequels to the same game that are incompatible with each other.

Star Wars games that are set in "what-if" versions of the Star Wars universe, like the Star Wars Infinities comics. (Those non-canon Star Wars comics take, as a premise, that something happened differently in one of the main movies; of course, any work that does this would intentionally contradict the canon and therefore would never be canon in the main Star Wars universe, but I think this could be fun.) Similar things could happen with other fantasy settings (and also with real history; what if the Romans failed to conquer Greece?).

A prequel to Tetris, describing the events that led up to the story of Tetris. (OK, maybe this one isn't as serious as the others.)
Half-Life 3.

Come on, someone had to. ;P
Post edited June 06, 2019 by Pherim
Independence War 3: eXtraterrestial Arrival (A brave Split pilot from the X series tests a captured Xenon device that turns out to be a machine that enables travelling between universes and they end up in The Badlands with only humans around who see you as the scary alien you are.)
Generals 2
Xenosaga series done properly: There's a year gap between Episode2 and Episode 3, that is not really explained. Shion in Ep3 seems quite moody for some reason.
It's too late for a proper Fallout 3, and I'm not sure what you'd even do for Arcanum 2, so I'll pass. Remasters with better graphics for Fallout 1-2 and Arcanum would be nice, using a modern, scalable 3D engine like Wasteland 2 or ATOM RPG, but with hexes.
Metal Gear Solid HD Collection for PC.